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Can You Use Niacinamide With Retinol?

The beauty world is abuzz with the magical effects of skincare powerhouses—retinol and niacinamide. Both of these ingredients have been extensively studied and are known for their positive effects on the skin. But can you mix niacinamide and retinol together? And if you can, what are the benefits of using niacinamide and retinol together for your skin? Let's delve into the science behind these ingredients and explore their combined use.

Benefits of Retinol for Skin

Retinol, a derivative of Vitamin A, is a proven warrior in the battle against aging. Scientifically speaking, retinol communicates with your skin cells, instructing them to behave like younger, healthier versions of themselves. As a cell-communicating ingredient, retinol has the capacity to influence collagen production, skin elasticity, and water retention—all factors that impact the appearance of fine lines and wrinkles.

A study published in the Journal of the American Academy of Dermatology concluded that topical retinol application can reduce signs of photoaging, including fine lines and wrinkles, pigmentation, laxity, and roughness.

What’s more? Retinol is also well-known for its acne-fighting properties. It helps regulate sebum production and accelerates skin cell turnover, preventing the clogged pores that lead to acne.

AccuFix Cosmetics Retin-oil Serum 0.2%, 0.5% and 1.0% (retinyl palmitate equivalent of retinol)

Benefits of Niacinamide for Skin

Niacinamide, also known as nicotinamide or vitamin B3, is a star player in the skincare world. It is a versatile, water-soluble vitamin that works with the natural substances in your skin to visibly improve enlarged pores, uneven skin tone, fine lines, and dullness.

Research published in the British Journal of Dermatology found that niacinamide can increase the production of ceramides, lipids that help maintain the skin's protective barrier. This results in improved skin hydration and a healthier, smoother skin texture.

Niacinamide has also been found to have anti-inflammatory properties, making it suitable for individuals with sensitive or acne-prone skin. It can help calm redness, soothe irritation, and reduce the severity of breakouts. In fact, some research suggests that niacinamide might be more effective than topical antibiotics in the treatment of acne.

AccuFix Cosmetics Crème B3-B5-E with 4% niacinamide

Can You Use Niacinamide With Retinol? | Benefits of Using Niacinamide and Retinol Together

Pairing retinol and niacinamide might just be the key to achieving that coveted flawless glow. But can you use niacinamide with retinol? The answer is a resounding yes!

Now that you know that you can, what are the benefits of using niacinamide and retinol together? Scientific evidence suggests that niacinamide and retinol work excellently together, addressing different skin concerns without canceling each other out. When used in conjunction, niacinamide can help mitigate the irritating effects of retinol, making retinol more tolerable for your skin. This synergy is particularly beneficial for those with sensitive skin who might otherwise struggle to incorporate retinol into their routine.

When used together, retinol and niacinamide can target multiple skin concerns simultaneously. Retinol provides anti-aging effects, while niacinamide helps regulate sebum production and improve the skin's barrier function. This combination can lead to a reduction in the appearance of fine lines, wrinkles, and hyperpigmentation, along with improved overall skin tone and texture.

How to Use Retinol and Niacinamide Together

Incorporating both retinol and niacinamide into your skincare routine is simpler than you might think. There are no set rules that you need to bear in mind when using both ingredients together, so you can customize your routine to whatever works best for you.

When using retinol, or any other retinoid, however, bear in mind that irritation and sensitivity can occur if you’re new to the ingredient. Always start with the lowest strength available and then slowly build up to whatever your skin is able to tolerate. While niacinamide can easily be used twice a day by most people, we wouldn’t recommend using retinol more than once a day; if you’re new to the ingredient, 2-3 times a week might also be enough.

Here’s a sample skincare routine that you can follow if you’re looking to incorporate both products into your skincare routine. This routine is great for people looking to fight pigmentation and the signs of aging, or adult-onset acne.

In the morning, wash your face with our Hydrating Gentle Daily Cleanser. Moisturize with Crème B3-B5-E, which contains 4% niacinamide along with panthenol, or vitamin B5 and vitamin E. Follow up with The Ultimate Sunscreen.



At night, replace the sunscreen with our Retin-oil Serum. Start by using the lowest strength and slowly build up to stronger variants as your skin adjusts to the product.



A few times a week, use the Salicylic Acid Cleanser or Resurfacing Face Wash as part of your night-time skincare routine to gently exfoliate your skin. The Salicylic Acid Cleanser is better for those with oily, acne-prone skin, while the Resurfacing Face Wash is better for those with normal to dry skin.



As always, remember that when it comes to skincare, consistency is key and also that everyone's skin is unique, and results can vary. If you still have questions, don’t hesitate to drop us a message on WhatsApp for a free skincare consultation: +92-302-222-8349.


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